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Following Palin's announcement, the Democratic National Committee blasted what it called her "bizarre behavior."

"Either Sarah Palin is leaving the people of Alaska high and dry to pursue her long shot national political ambitions or she simply can't handle the job now that her popularity has dimmed and oil revenues are down," DNC spokesman Brad Woodhouse said.

"Either way, her decision to abandon her post and the people of Alaska who elected her continues a pattern of bizarre behavior that more than anything else may explain the decision she made today."

Republican strategist and CNN contributor Ed Rollins said, to a certain extent, Palin's announcement makes her look "terribly inept."

"I think everyone is shocked by this, and I think to a certain extent everyone is going to assume there's another story. You don't just quit with a year and a half to go. You certainly don't do this as a stepping stone to run for president. You finish the job that you're in, and obviously she's not doing that," he said.

"I think people are going to be very suspicious because of the timing. You don't quit on the Friday of a three-day holiday. If you are going to do this, you think it through, you give a good speech," Rollins said.